Update on ADNI: Amyloid Present Even Without Memory Issues

November 9, 2012

Approximately 30% of healthy people in their mid-70s without memory problems nevertheless have amyloid on brain imaging, according to the latest results from the Alzheimer's Disease Neuroimaging Initiative (ADNI).

"We showed that using different kinds of biomarkers, especially amyloid imaging and cerebrospinal fluid (CSF) measurements, can demonstrate the presence of amyloid in subjects who seemed healthy and had no memory complaints," said Michael W. Weiner, MD, professor of radiology, medicine, psychiatry and neurology, University of California at San Francisco, and principal investigator of ADNI.