Nicotine Vaccine Promising for Smoking Cessation

February 27, 2013

An experimental nicotine vaccine reduces the amount of nicotine that reaches the brain and binds to nicotinic acetylcholine receptors (nAChRs), helping to reduce cigarette use and cravings, new research shows. However, at least 1 expert has some misgivings about its potential as an effective treatment.

"It appears that the vaccine may help with smoking cessation, but likely as an adjunct to existing pharmacology or psychological treatments," Irina Esterlis, PhD, assistant professor of psychiatry and diagnostic radiology, Yale University, New Haven, Connecticut, told Medscape Medical News.