Lymphoseek Approved in US for Breast Cancer, Melanoma

March 14, 2013

A novel receptor-targeted radioactive tracer for intraoperative lymphatic mapping (ILM) — technetium Tc 99m tilmanocept (Lymphoseek, Navidea Biopharmaceuticals) — has been approved by the US Food and Drug Administration (FDA). It is indicated for use in patients with breast cancer or melanoma who are undergoing surgery to remove tumor-draining lymph nodes.

ILM is widely used for staging in patients with breast cancer and melanoma who are clinically node-negative; the mapping can detect whether any nodes contain cancer cells.