Radiolabeled Small Molecules Show Promise in Prostate Cancer Early Detection

March 21, 2013

Radiolabeled small molecules targeting prostate-specific membrane antigen (PSMA) are well-tolerated tools for detection of metastatic prostate cancer, according to data published in the March 2013 issue of the Journal of Nuclear Medicine.

The study consisted of a phase I clinical trial utilizing an open-label, crossover design. Seven men aged 53 to 86 with confirmed prostate cancer and six healthy volunteers were selected for intravenous administration of two different agents designed to target PSMA, a well-known marker for prostate cancer.