Alzheimer’s likely takes more than two decades to develop

March 21, 2013

A prospective study published in the April issue of The Lancet showed how beta-amyloid burden in the brain relates to the long-term progression of cognitive decline, cerebral atrophy and other indications of Alzheimer’s disease (AD). “Beta-amyloid deposition is slow and protracted, likely to extend for more than two decades,” the authors wrote.

“Such predictions of the rate of preclinical changes and the onset of the clinical phase of AD will facilitate the design and timing of therapeutic interventions aimed at modifying the course of this illness,” wrote Victor L. Villemagne, MD, of the Australian Imaging Biomarkers and Lifestyle Research Group, and colleagues.