SPECT smokes out cigarette-related changes in the lung leading to COPD

April 9, 2013

Ventilation and perfusion (V/Q) SPECT could one day be used to track the early warning signs of cigarette smoke-induced chronic obstructive pulmonary disease (COPD) by documenting telltale airflow dysfunction, according to a study published in the April issue of The Journal of Nuclear Medicine .

Brian N. Jobse, PhD, from the department of medicine and division of respirology at McMaster University in Hamilton, Ontario, Canada, and colleagues, leveraged V/Q SPECT to provide quantitative analysis of the progression of airflow impairment associated with COPD in mice exposed to daily cigarette smoke before CT could pick up any structural changes in the lungs.