MRI, PET show sleep disorder, Alzheimer's link

May 21, 2013

Using structural MRI and PET, researchers from New York University (NYU) may have found a link between sleep-disordered breathing and markers in cerebrospinal fluid that could indicate risk of Alzheimer's disease.

The findings add to the debate over whether Alzheimer's disease in its preclinical stages could lead to sleep-disordered breathing and explain the increased prevalence of sleep-disordered breathing in older people.

The study enrolled 68 cognitively normal elderly patients (mean age, 71.4), who underwent two nights of home monitoring for sleep-disordered breathing and were tested for at least one indicator of Alzheimer's disease.