PET/MR shows promise for pulmonary nodule evaluation

June 18, 2013

The launch of PET/MR imaging has renewed interest in the role of MR and PET/MR in pulmonary nodule evaluation. The hybrid modality demonstrated high sensitivity in the detection of FDG-avid nodules and nodules 5 cm or larger, according to a study published online June 4 in Radiology.  

Although CT has served as the gold standard in the detection of lung nodules, its sensitivity in the discrimination of malignant from benign nodules is limited. Meanwhile, PET/MR has emerged and prompted interest in its potential utility, which pairs the high contrast and functional information of MR with metabolic PET activity. Hersh Chandarana, MD, from the department of radiology at New York University Langone Medical Center in New York City, and colleagues devised a study to evaluate MR, PET and PET/MR in the detection of lung nodules, using PET/CT as a reference standard.