NaF-PET/CT beats scintigraphy, SPECT/CT for bone metastases

July 9, 2013

Sodium fluoride (NaF) PET/CT provides greater sensitivity and specificity for the detection of bone metastases than planar bone scintigraphy and SPECT/CT, according to a new pilot study from Copenhagen University Hospital.

In the comparison, planar bone scintigraphy also had a relatively high number of equivocal scans compared to NaF-PET/CT, which could reflect uncertainty in reading planar bone scintigraphy due to the modality's low sensitivity and specificity, the researchers concluded.